Fig. 1 · Structure
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Poly(deoxyadenylic-thymidylic) acid sodium
Synthetic DNA Polymer
Poly(deoxyadenylic-thymidylic) acid sodium is a synthetic DNA polymer that serves as a substrate for ribonucleic acid polymerase, enabling the assessment of both bound and free enzyme activity. This polymer is recognized by various pattern recognition receptors (PRRs), including cGAS, AIM2, and DDX41, activating the production of type I interferons. Its applications extend to cancer research and studies on viral infections, making it a valuable tool in understanding immune responses and transcriptional processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 86828-69-5 |
| Applications | Synthetic DNA Polymer |
| Formula | (C10H15N2O8P.C10H14N5O6P)x.xNa |
| Synonyms | Poly(dA:dT) sodium |
| SMILES | O=C(NC1=O)N(C=C1C)[C@](C[C@@H]2O)([H])O[C@@H]2CO[P](O)(O)=O.NC3=C4C(N([C@](C[C@@H]5O)([H])O[C@@H]5CO[P](O)(O)=O)C=N4)=NC=N3.[Na].[x].[x] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.