Polygalaxanthone VIII

Catalog No.: A96871
Natural Product
Polygalaxanthone VIII is a natural product derived from Polygala tenuifolia, exhibiting potential neuroprotective and anti-inflammatory activities. Its mechanisms include inhibition of oxidative stress and modulation of inflammatory pathways, making it a valuable compound for research focused on neurodegenerative diseases and conditions characterized by chronic inflammation. This compound serves as a useful tool in pharmacological studies aimed at uncovering therapeutic avenues in neuroscience and immunology.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPolygalaxanthone VIII is a natural product derived from Polygala tenuifolia, exhibiting potential neuroprotective and anti-inflammatory activities. Its mechanisms include inhibition of oxidative stress and modulation of inflammatory pathways, making it a valuable compound for research focused on neurodegenerative diseases and conditions characterized by chronic inflammation. This compound serves as a useful tool in pharmacological studies aimed at uncovering therapeutic avenues in neuroscience and immunology.
Product Information
Catalog NumA96871
FormulaC25H28O15
Molecular Weight568.48
CAS Number857859-79-1
SMILESOC1=C2C(OC3=CC(O)=C(OC)C=C3C2=O)=CC(O)=C1[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@H]5[C@H]([C@@H]([C@@H](CO5)O)O)O
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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