Fig. 1 · Structure
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Pomalidomide-d5
Stable Isotope
Pomalidomide-d5 is a deuterium-labeled analog of Pomalidomide, a third-generation immunomodulatory agent. By acting as a molecular glue, Pomalidomide-d5 interacts with the E3 ligase cereblon, promoting the degradation of critical Ikaros transcription factors. This compound is valuable for studies in drug metabolism, pharmacokinetics, and mechanistic investigations related to multiple myeloma and other hematological malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1377838-49-7 |
| Applications | Stable Isotope |
| Formula | C13H6D5N3O4 |
| Molecular Weight | 278.27 |
| Synonyms | CC-4047-d5 |
| SMILES | NC1=C2C(C(N(C2=O)C3(C(NC(C([2H])(C3([2H])[2H])[2H])=O)=O)[2H])=O)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.