Pomalidomide-d5 is a deuterium-labeled analog of Pomalidomide, a third-generation immunomodulatory agent. By acting as a molecular glue, Pomalidomide-d5 interacts with the E3 ligase cereblon, promoting the degradation of critical Ikaros transcription factors. This compound is valuable for studies in drug metabolism, pharmacokinetics, and mechanistic investigations related to multiple myeloma and other hematological malignancies.
Pomalidomide-d5 is a deuterium-labeled analog of Pomalidomide, a third-generation immunomodulatory agent. By acting as a molecular glue, Pomalidomide-d5 interacts with the E3 ligase cereblon, promoting the degradation of critical Ikaros transcription factors. This compound is valuable for studies in drug metabolism, pharmacokinetics, and mechanistic investigations related to multiple myeloma and other hematological malignancies.
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