Fig. 1 · Structure

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Pomalidomide-piperazine

Active Compound

Pomalidomide-piperazine is an active compound that serves as a critical building block for the synthesis of E3 ligands utilized in PROTAC (Proteolysis Targeting Chimeras) development. This compound facilitates targeted protein degradation by linking a protein of interest to an E3 ubiquitin ligase, promoting a novel approach to protein modulation. Its application is significant in drug discovery and therapeutic research focused on precision medicine.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2154342-57-9
Applications Active Compound
Formula C17H18N4O4
Molecular Weight 342.35
SMILES
O=C1NC(C(CC1)N2C(C3=CC=CC(N4CCNCC4)=C3C2=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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