Fig. 1 · Structure
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Pomonic acid
ACAT Inhibitor
Pomonic acid is an acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor that effectively reduces the esterification of free cholesterol to cholesteryl esters. By decreasing intracellular cholesteryl ester accumulation, it serves as a valuable tool for studying lipid metabolism disorders. Pomonic acid is particularly relevant in research focused on atherosclerosis and related cardiovascular diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 13849-90-6 |
| Applications | ACAT Inhibitor |
| Formula | C30H46O4 |
| Molecular Weight | 470.68 |
| SMILES | O=C([C@]12CC[C@H]([C@@](O)([C@H]1C3=CC[C@H]4[C@@](CC[C@H]5C(C)(C(CC[C@@]54C)=O)C)([C@@]3(CC2)C)C)C)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.