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Porcn-IN-2

Porcn Inhibitor

Porcn-IN-2 is a potent Porcupine (Porcn) inhibitor, demonstrating an IC50 of 0.05 nM. This compound effectively disrupts the Wnt signaling pathway, making it a valuable tool for research into various cancers, including sarcoma, melanoma, skin cancer, hematological tumors, lymphoma, carcinoma, and leukemia. Its ability to modulate Wnt signaling provides significant insights into tumorigenesis and potential therapeutic approaches.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1900754-65-5
Applications	Porcn Inhibitor
Formula	C₂₄H₁₇F₃N₆O
Molecular Weight	462.43
SMILES	N#CC1=CC=C(C2=CC=C(NC(CN3C=NC(C4=CC(C(F)(F)F)=NC=C4)=C3C)=O)N=C2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.