Fig. 1 · Structure
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POSH-IN-1
POSH Inhibitor
POSH-IN-1 is a potent inhibitor of the POSH polypeptide, specifically targeting its ubiquitin ligase activity with an IC50 of 900 nM. This compound is primarily utilized in research focused on protein ubiquitination processes and their implications in cellular signaling pathways. Its role in modulating POSH activity makes it a valuable tool for studying disease mechanisms linked to aberrant ubiquitin signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 328960-84-5 |
| Applications | POSH Inhibitor |
| Formula | C14H8FNO3S |
| Molecular Weight | 289.28 |
| SMILES | O=C1S/C(C(N1)=O)=C\C2=CC=C(C3=CC=C(F)C=C3)O2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.