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Povorcitinib-d6

Stable Isotope

Povorcitinib-d6 is a deuterium-labeled form of Povorcitinib, a selective and potent inhibitor of JAK1. This compound is instrumental in investigating the pathophysiological mechanisms underlying cutaneous lupus erythematosus (CLE) and lichen planus (LP) by effectively reducing inflammatory lesions such as abscesses and nodules. Its stable isotope labeling allows for enhanced tracking and analysis in various biological research applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3029304-24-0
Applications	Stable Isotope
Formula	C₂₃H₁₆D₆F₅N₇O
Molecular Weight	513.50
Synonyms	INCB54707-d6
SMILES	N#CCC1(N2C=C(C3=C(C([2H])([2H])[2H])NN=C3C([2H])([2H])[2H])C=N2)CN(C4=C(C=C(C(F)=C4)C(N[C@@H](C)C(F)(F)F)=O)F)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.