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Biological Activity
PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR, FGFR and Src family activities with nanomolar IC50 values.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.91 mL | 109.57 mL | 219.14 mL |
| 0.5 mM | 4.38 mL | 21.91 mL | 43.83 mL |
| 1 mM | 2.19 mL | 10.96 mL | 21.91 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
*The above data is based on the productmolecular weight 456.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20906 |
|---|---|
| CAS No. | 212391-58-7 |
| Formula | C22H19Cl2N5O2 |
| M. Wt | 456.32 |
| Purity | >98% |
| Synonyms | PP 58, PP-58 |
| SMILES | NCCOC1=CC=C(NC(N=C2N3C)=NC=C2C=C(C4=C(Cl)C=CC=C4Cl)C3=O)C=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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