PP58

Catalog No.: A20906

PP58

PP58 Chemical Structure

CAS NO. 212391-58-7

PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR, FGFR and Src family activities with nanomolar IC50 values.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $151.00

Special Price $120.80

5 mg

Regular Price: $454.00

Special Price $363.20

10 mg

Regular Price: $773.00

Special Price $618.40

50 mg

Regular Price: $2,318.00

Special Price $1,854.40

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Biological Activity

PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR, FGFR and Src family activities with nanomolar IC50 values.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.91 mL 109.57 mL 219.14 mL
0.5 mM 4.38 mL 21.91 mL 43.83 mL
1 mM 2.19 mL 10.96 mL 21.91 mL
5 mM 0.44 mL 2.19 mL 4.38 mL

*The above data is based on the productmolecular weight 456.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20906
CAS No. 212391-58-7
Formula C22H19Cl2N5O2
M. Wt 456.32
Purity >98%
Synonyms PP 58, PP-58
SMILES NCCOC1=CC=C(NC(N=C2N3C)=NC=C2C=C(C4=C(Cl)C=CC=C4Cl)C3=O)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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