Fig. 1 · Structure

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ppGalNAc-T2-IN-1

ppGalNAc-T2Inhibitor

ppGalNAc-T2-IN-1 is a selective inhibitor of Polypeptide N-acetyl-galactosaminyltransferase 2 (ppGalNAc-T2), exhibiting an IC50 of 7.11 μM. This reagent is valuable for investigating the role of ppGalNAc-T2 in metabolic and neurodevelopmental disorders. Its application in research can help elucidate the enzyme's involvement in glycosylation processes, potentially leading to insights into therapeutic strategies for related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1112431-86-3
Applications ppGalNAc-T2Inhibitor
Formula C22H15N3O2S
Molecular Weight 385.44
SMILES
N#CC1=C(SCCN2C(C3=C(C2=O)C=CC=C3)=O)N=C(C4=CC=CC=C4)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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