PPO-IN-1 is a potent inhibitor of protoporphyrinogen IX oxidase (PPO), exhibiting a Ki value of 2.5 nM. This compound serves as a valuable click chemistry reagent, featuring an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. Its primary biological activity makes it useful for studying pathways involving heme biosynthesis and investigating potential therapeutic applications in diseases related to PPO dysregulation.
PPO-IN-1 is a potent inhibitor of protoporphyrinogen IX oxidase (PPO), exhibiting a Ki value of 2.5 nM. This compound serves as a valuable click chemistry reagent, featuring an alkyne group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. Its primary biological activity makes it useful for studying pathways involving heme biosynthesis and investigating potential therapeutic applications in diseases related to PPO dysregulation.
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