Fig. 1 · Structure

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ppTG21

Endosomolytic Agent

ppTG21 is an endosomolytic agent that enhances the intracellular delivery of ribonucleoproteins (RNPs) such as Cas9-2lig-1NLS and Cas9-ASGPrL. By promoting endosomal escape, ppTG21 enables receptor-mediated, cell-type specific gene editing in cancer cells without the need for electroporation or transfection reagents. Its applications are significant in the field of gene editing research, allowing for targeted modifications within specific cellular contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 380480-77-3
Applications Endosomolytic Agent
Formula C115H173N31O22
Molecular Weight 2341.80

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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