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Biological Activity
PQM130, a Feruloyl-Donepezil Hybrid compound with brain penatration, is a multitarget drug candidate against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity. PQM130 acts as a neuroprotective compound for anti-AD drug development.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.22 mL | 131.08 mL | 262.15 mL |
| 0.5 mM | 5.24 mL | 26.22 mL | 52.43 mL |
| 1 mM | 2.62 mL | 13.11 mL | 26.22 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.24 mL |
*The above data is based on the productmolecular weight 381.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18835 |
|---|---|
| CAS No. | 2089415-51-8 |
| Formula | C23H27NO4 |
| M. Wt | 381.46 |
| Purity | >98% |
| Synonyms | PQM 130. PQM-130 |
| SMILES | O=C(OCC1CCN(CC2=CC=CC=C2)CC1)/C=C/C3=CC=C(O)C(OC)=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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