Fig. 1 · Structure
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PqsR/LasR-IN-3
PqsR/LasR Inhibitor
PqsR/LasR-IN-3 is a potent inhibitor targeting the PqsR and LasR signaling systems in Pseudomonas aeruginosa. This compound exhibits significant biological activity, making it valuable for research applications aimed at understanding quorum sensing and biofilm formation in this pathogenic bacterium. Additionally, it shows hERG inhibition with an IC50 of 109.01 µM, highlighting its potential impact on cardiac safety in biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2581109-51-3 |
| Applications | PqsR/LasR Inhibitor |
| Formula | C14H17NO5S |
| Molecular Weight | 311.35 |
| SMILES | O=C(NC1CCOC1=O)CCCS(=O)(C2=CC=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.