Pradefovir mesylate

Catalog No.: A21644

Pradefovir mesylate

Pradefovir mesylate Chemical Structure

CAS NO. 625095-61-6

Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.

Availability: In stock

Package Price Qty
5 mg
$495.00
10 mg
$853.00
50 mg
$2,530.00
100 mg
$5,060.00
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Biological Activity

Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.23 mL 96.17 mL 192.34 mL
0.5 mM 3.85 mL 19.23 mL 38.47 mL
1 mM 1.92 mL 9.62 mL 19.23 mL
5 mM 0.38 mL 1.92 mL 3.85 mL

*The above data is based on the productmolecular weight 519.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21644
CAS No. 625095-61-6
Formula C18H23ClN5O7PS
M. Wt 519.9
Purity >98%
Synonyms Remofovir mesylate
SMILES NC1=C2N=CN(CCOC[[email protected]]3(OCC[[email protected]@H](C4=CC=CC(Cl)=C4)O3)=O)C2=NC=N1.CS(=O)(O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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