Pravastatin sodium

Catalog No.: A11912

HMG-CoA reductase inhibitor

Pravastatin sodium

Pravastatin sodium Chemical Structure

CAS NO. 81131-70-6

Pravastatin sodium is a water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties.

Availability: In stock

Package Price Qty
25 mg

Regular Price: $40.00

Special Price $36.00

50 mg

Regular Price: $60.00

Special Price $54.00

100 mg

Regular Price: $100.00

Special Price $90.00

250 mg

Regular Price: $180.00

Special Price $162.00

10mM * 1mL in DMSO

Regular Price: $66.00

Special Price $59.40

Warning WARNING: Attention California Residents: This product can expose you to chemicals including Adriamycin, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Pravastatin sodium is a water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties.
Targets
HMG-CoA reductase
5.6 μM
In vitro DMSO 89 mg/mL (199.32 mM)
Water 89 mg/mL (199.32 mM)
Ethanol 12 mg/mL (26.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.4 mL 111.98 mL 223.96 mL
0.5 mM 4.48 mL 22.4 mL 44.79 mL
1 mM 2.24 mL 11.2 mL 22.4 mL
5 mM 0.45 mL 2.24 mL 4.48 mL

*The above data is based on the productmolecular weight 446.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11912
Actions Inhibitor
M. Wt 446.51
Formula C23H35NaO7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 81131-70-6
Synonyms Eptastatin sodium
SMILES CC[[email protected]](C)C(=O)O[[email protected]]1C[[email protected]@H](C=C2[[email protected]]1[[email protected]]([[email protected]](C=C2)C)CC[[email protected]](C[[email protected]](CC(=O)[O-])O)O)O.[Na+]

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