Prazosin HCl

Prazosin HCl is an α1 and α2B-adrenoceptor antagonist. Also a potent antagonist at the melatonin MT3 receptor (Ki = 10.2 nM).
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Product Name Price Stock Qty
Prazosin HCl 100mg
In stock
Prazosin HCl 250mg
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Prazosin HCl 500mg
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Prazosin HCl 1000mg
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Prazosin HCl has been cited by 1 publications
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Biological Activity
    Discription Prazosin HCl is an α1 and α2B-adrenoceptor antagonist. Also a potent antagonist at the melatonin MT3 receptor (Ki = 10.2 nM).
    Target Value
    Chemical Information
    Catalog Num A11914
    Formula C19H21N5O4.HCl
    Molecular Weight 419.87
    CAS Number 19237-84-4
    SMILES COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro DMSO Warmed: 4 mg/mL (9.52 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 23.82 mL 119.08 mL 238.17 mL
    0.5 mM 4.76 mL 23.82 mL 47.63 mL
    1 mM 2.38 mL 11.91 mL 23.82 mL
    5 mM 0.48 mL 2.38 mL 4.76 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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