Fig. 1 · Structure
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Pregnenolone-13C2,d2
Stable Isotope
Pregnenolone-13C2,d2 is a stable isotope-labeled form of Pregnenolone, which serves as a critical precursor for various steroid hormones. This neurosteroid functions as a selective inhibitor of the cannabinoid CB1 receptor, mitigating the effects of tetrahydrocannabinol (THC) associated with CB1 receptor activation. Additionally, Pregnenolone-13C2,d2 is recognized for its ability to activate the TRPM3 channel and demonstrates weak activity on TRPM1 channels. Its unique isotopic labeling makes it a valuable tool for research applications in neuropharmacology and steroid biochemistry.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2483824-26-4 |
| Applications | Stable Isotope |
| Formula | C1913C2H30D2O2 |
| Molecular Weight | 320.48 |
| Synonyms | 3β-Hydroxy-5-pregnen-20-one-13C2; d2 |
| SMILES | C[C@@](C1=CC2)(CC[C@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC([2H])([2H])[C@@H]4[13C]([13CH3])=O)([H])[C@]4(C)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.