Fig. 1 · Structure
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Pregnenolone-d4-1
Stable Isotope
Pregnenolone-d4-1 is a deuterium-labeled derivative of pregnenolone, a key neurosteroid and precursor to steroid hormones, including steroid ketones. It selectively inhibits cannabinoid CB1 receptors, counteracting the effects of tetrahydrocannabinol (THC) and providing potential neuroprotective benefits against cannabis intoxication. Additionally, pregnenolone-d4-1 activates TRPM3 channels and may exhibit weak activation of TRPM1 channels, making it useful in research related to neurobiology and cannabinoid signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 61574-54-7 |
| Applications | Stable Isotope |
| Formula | C21H28D4O2 |
| Molecular Weight | 320.50 |
| Synonyms | 3β-Hydroxy-5-pregnen-20-one-d4-1 |
| SMILES | C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([2H])C(C([2H])([2H])[2H])=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.