Preptin (rat)

Catalog No.: A38277
Peptide
Preptin (rat) is an osteogenic peptide derived from the pancreatic beta-cell, specifically representing the Asp69-Leu102 segment of pro-IGF-II. This peptide plays a significant role in bone metabolism and has been shown to stimulate osteoblast differentiation and activity. Preptin is utilized in research applications aimed at understanding bone development, cellular signaling pathways, and the potential therapeutic effects in metabolic bone disorders.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPreptin (rat) is an osteogenic peptide derived from the pancreatic beta-cell, specifically representing the Asp69-Leu102 segment of pro-IGF-II. This peptide plays a significant role in bone metabolism and has been shown to stimulate osteoblast differentiation and activity. Preptin is utilized in research applications aimed at understanding bone development, cellular signaling pathways, and the potential therapeutic effects in metabolic bone disorders.
Product Information
Catalog NumA38277
FormulaC181H268N48O51
Molecular Weight3932.36
CAS Number315197-73-0
SequenceAsp-Val-Ser-Thr-Ser-Gln-Ala-Val-Leu-Pro-Asp-Asp-Phe-Pro-Arg-Tyr-Pro-Val-Gly-Lys-Phe-Phe-Lys-Phe-Asp-Thr-Trp-Arg-Gln-Ser-Ala-Gly-Arg-Leu
Sequence shorteningDVSTSQAVLPDDFPRYPVGKFFKFDTWRQSAGRL
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