Fig. 1 · Structure

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Presenilin 1 (349-361)

Active Petide

Presenilin 1 (349-361) is an active peptide consisting of amino acids 349–361, which is known to be a substrate for phosphorylation by glycogen synthase kinase-3β (GSK3β) in vitro. This peptide plays a significant role in the study of Alzheimer's disease and other neurodegenerative disorders by investigating the functional implications of presenilin 1 activity. Its ability to be phosphorylated allows researchers to explore signaling pathways involved in cellular processes and disease mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 956004-39-0
Applications Active Petide
Formula C56H93N21O19
Molecular Weight 1364.47
SMILES
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C(CN)=O)CCC1)CC2=CN=CN2)=O)CCCNC(=N)N)=O)CO)=O)[C@@H](C)O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)C)=O)C)=O)CCCNC(=N)N)=O)CO)=O)CCC(O)=O)=O)CCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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