Pretomanid-d4 is a deuterium-labeled derivative of Pretomanid, an antibiotic specifically targeting Mycobacterium tuberculosis (MTB) in the context of multi-drug-resistant tuberculosis. Exhibiting a sub-micromolar minimum inhibitory concentration (MIC), Pretomanid demonstrates significant antimicrobial activity, with MIC values against various MTB strains ranging from 0.015 to 0.25 μg/mL. This stable isotope is valuable for pharmacokinetic studies and metabolic profiling in tuberculosis research.
Pretomanid-d4 is a deuterium-labeled derivative of Pretomanid, an antibiotic specifically targeting Mycobacterium tuberculosis (MTB) in the context of multi-drug-resistant tuberculosis. Exhibiting a sub-micromolar minimum inhibitory concentration (MIC), Pretomanid demonstrates significant antimicrobial activity, with MIC values against various MTB strains ranging from 0.015 to 0.25 μg/mL. This stable isotope is valuable for pharmacokinetic studies and metabolic profiling in tuberculosis research.
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