Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells with an IC50 of ~350 nM for catecholamine secretion in PC12 pheochromocytoma cells, acting in a noncompetitive manner specifically at the nicotinic cholinergic receptor.
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| Description | Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells with an IC50 of ~350 nM for catecholamine secretion in PC12 pheochromocytoma cells, acting in a noncompetitive manner specifically at the nicotinic cholinergic receptor. |
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| Catalog Num | A23449 |
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| Formula | C112H178N36O27 |
| Molecular Weight | 2460.84 |
| CAS Number | 150238-87-2 |
| Sequence | Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2 |
| Sequence shortening | ARLDVASEFRKKWNKWALSR-NH2 |
| Synonyms | ProAM N20, Human; PAMP-20, human |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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