Fig. 1 · Structure
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Probimane
Anticancer Agent
Probimane (AT-2153) is a potent anticancer agent that exhibits significant cytotoxic activity. It has demonstrated effectiveness against various tumor models, including mouse tumors S37, S180, Lewis lung carcinoma, L1210, as well as human pulmonary adenocarcinoma when heterotransplanted into nude mice. This compound is primarily utilized in cancer research to explore therapeutic strategies and mechanisms of action against diverse cancer types.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 108093-90-9 |
| Applications | Anticancer Agent |
| Formula | C21H34N6O6 |
| Molecular Weight | 466.53 |
| Synonyms | AT-2153 |
| SMILES | O=C1N(CN2CCOCC2)C(CN(CC(C)N3CC(N(CN4CCOCC4)C(C3)=O)=O)C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.