Fig. 1 · Structure

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Progranulin modulator-3

Progranulin Modulator

Progranulin modulator-3 (compound C40) is a brain-penetrant, orally active inducer of progranulin (PGRN). This reagent plays a significant role in neurobiology by enhancing PGRN levels, which are implicated in neurodegenerative diseases and brain health. It is particularly valuable for research applications focused on neurological disorders and the therapeutic potential of PGRN modulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Inducer
CAS Number 371116-39-1
Applications Progranulin Modulator
Formula C18H12N2O3
Molecular Weight 304.30
SMILES
O=C(C1=CC=CO1)NC2=CC=C3C(N=C(C4=CC=CC=C4)O3)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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