Fig. 1 · Structure
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Promestriene
Estrogen Agonist
Promestriene is a synthetic diethyl-ether derivative of estradiol that functions as a selective estrogen agonist. It demonstrates significant efficacy in the treatment of vaginal atrophy while exhibiting minimal systemic absorption. This compound is primarily utilized in research related to local estrogenic effects and women’s health studies, particularly in the context of post-menopausal therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 39219-28-8 |
| Applications | Estrogen Agonist |
| Formula | C22H32O2 |
| Molecular Weight | 328.49 |
| SMILES | C[C@@]12[C@@H](OC)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OCCC)=C4)[C@@]3([H])CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.