Fig. 1 · Structure
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Promethazine-d6 hydrochloride
Deuterated Promethazine
Promethazine-d6 hydrochloride is a deuterated form of Promethazine hydrochloride, functioning as a histamine H1 receptor antagonist. This compound exhibits potent antihistaminic activity, making it valuable for studies related to allergic reactions, sleep disorders, and motion sickness. Its deuterated nature aids in isotopic labeling for pharmacokinetic and metabolic studies in chemical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1189947-02-1 |
| Applications | Deuterated Promethazine |
| Formula | C17H15D6ClN2S |
| Molecular Weight | 326.92 |
| Synonyms | (±)-Promethazine-d6 hydrochloride |
| SMILES | [2H]C([2H])([2H])N(C([2H])([2H])[2H])C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.