Fig. 1 · Structure
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Propentofylline
phosphodiesterase inhibitor
Propentofylline is a phosphodiesterase inhibitor that enhances adenosine signaling by inhibiting its uptake and blocking phosphodiesterase activity. This compound demonstrates neuroprotective, antiproliferative, and anti-inflammatory properties, making it relevant for research on cognitive enhancement and dementia. It has shown potential in improving cognition and reducing the severity of symptoms in conditions such as Alzheimer's disease and vascular dementia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 55242-55-2 |
| Applications | phosphodiesterase inhibitor |
| Formula | C15H22N4O3 |
| Molecular Weight | 306.36 |
| Synonyms | HWA 285 |
| SMILES | O=C1C2=C(N(C)C(N1CCCCC(C)=O)=O)N=CN2CCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.