Fig. 1 · Structure
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Propylthiouracil
Antithyroid Agent
Propylthiouracil is an antithyroid agent that functions primarily as a thyroperoxidase and type-1 deiodinase (DIO1) inhibitor. This compound is widely utilized in research related to Graves' disease and hyperthyroidism, demonstrating significant biological activity in regulating thyroid hormone synthesis and metabolism. Its ability to manage hyperthyroid conditions makes it a valuable tool in endocrine research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 51-52-5 |
| Applications | Antithyroid Agent |
| Formula | C7H10N2OS |
| Molecular Weight | 170.23 |
| Synonyms | 6-n-Propylthiouracil; 6-Propyl-2-thiouracil; PTU |
| SMILES | O=C(C=C(CCC)N1)NC1=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.