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PROTAC BCL6/GSPT1 Degrader-1

BCL6/GSPT1 Degrader

PROTAC BCL6/GSPT1 Degrader-1 is a dual-target PROTAC that effectively degrades both BCL6 and GSPT1 proteins. This compound is associated with the inhibition of cell proliferation, along with the induction of DNA damage, cell cycle arrest, and apoptosis, specifically in diffuse large B-cell lymphoma. It serves as a valuable tool for research into tumor biology, particularly in the context of lymphoma and related malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3039500-55-2
Applications	BCL6/GSPT1 Degrader
Formula	C₄₇H₅₇ClN₁₀O₁₃
Molecular Weight	1005.47
SMILES	O=C(COC1=CC2=C(N(C)C1=O)C(OC)=CC(NC3=NC(N4CCC(CC4)C(NCCOCCOCCOCCOCCNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)=NC=C3Cl)=C2)NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.