PROTAC BCL6/GSPT1 Degrader-1

Catalog No.: A25356
BCL6/GSPT1 Degrader
PROTAC BCL6/GSPT1 Degrader-1 is a dual-target PROTAC that effectively degrades both BCL6 and GSPT1 proteins. This compound is associated with the inhibition of cell proliferation, along with the induction of DNA damage, cell cycle arrest, and apoptosis, specifically in diffuse large B-cell lymphoma. It serves as a valuable tool for research into tumor biology, particularly in the context of lymphoma and related malignancies.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPROTAC BCL6/GSPT1 Degrader-1 is a dual-target PROTAC that effectively degrades both BCL6 and GSPT1 proteins. This compound is associated with the inhibition of cell proliferation, along with the induction of DNA damage, cell cycle arrest, and apoptosis, specifically in diffuse large B-cell lymphoma. It serves as a valuable tool for research into tumor biology, particularly in the context of lymphoma and related malignancies.
Product Information
Catalog NumA25356
FormulaC47H57ClN10O13
Molecular Weight1005.47
CAS Number3039500-55-2
SMILESO=C(COC1=CC2=C(N(C)C1=O)C(OC)=CC(NC3=NC(N4CCC(CC4)C(NCCOCCOCCOCCOCCNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)=NC=C3Cl)=C2)NC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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