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PROTAC BRD4 ligand-3

Ligand for Target Protein for PROTAC

PROTAC BRD4 ligand-3 is a specialized ligand designed to engage the BRD4 protein for targeted protein degradation applications via the PROTAC (proteolysis-targeting chimeras) technology. This compound facilitates the synthesis of PROTAC BRD4 Degrader-27, providing a valuable tool for research in targeted therapeutics and the study of BRD4-related pathways in various diseases, including cancer. Its ability to promote the selective degradation of BRD4 makes it instrumental for investigating the functional role of this protein in cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1445994-28-4
Applications	Ligand for Target Protein for PROTAC
Formula	C₂₀H₁₅F₂N₃O₂
Molecular Weight	367.35
SMILES	CN1C=C(C2=C(C1=O)NC=C2)C3=CC(N)=CC=C3OC4=CC=C(C=C4F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.