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PROTAC CDK9/CycT1 Degrader-2

CDK9 Inhibitor

PROTAC CDK9/CycT1 Degrader-2 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9), exhibiting an IC50 of 45 nM. This compound promotes targeted protein degradation, thereby modulating transcriptional regulation and influencing cellular processes associated with gene expression. It is valuable for research applications focused on cancer biology and therapeutic development by addressing dysregulated CDK9 activity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3020773-91-2
Applications	CDK9 Inhibitor
Formula	C₃₀H₃₆N₄O₆S₂
Molecular Weight	612.76
SMILES	O=C1OC2=CC(OCCCN3CCC(CC3)C(NC4=NC=C(S4)SCC5=NC=C(O5)C(C)(C)C)=O)=CC(O)=C2C(C)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.