Fig. 1 · Structure
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PROTAC CDK9 degrader-7
CDK9 PROTAC
PROTAC CDK9 degrader-7 is a designed degradate that specifically targets cyclin-dependent kinase 9 (CDK9). This compound facilitates the degradation of CDK9 through the proteasomal pathway, effectively reducing its cellular levels. Its biological activity makes it a valuable tool for research applications focused on investigating CDK9's role in transcription regulation and its implications in cancer therapy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2935587-90-7 |
| Applications | CDK9 PROTAC |
| Formula | C43H50Cl2N8O9 |
| Molecular Weight | 893.81 |
| SMILES | O=C(NCCCCCCCCCCCC(N1CCC(CC1)NC(C2=NNC=C2NC(C3=C(C=CC=C3Cl)Cl)=O)=O)=O)COC4=CC=CC5=C4C(N(C5=O)C6CCC(NC6=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.