Fig. 1 · Structure
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PROTAC DDR1 degrader-1
DDR1 PROTAC Degrader
PROTAC DDR1 degrader-1 is a PROTAC-based degrader designed to selectively target the discoidin domain receptor 1 (DDR1) for proteasomal degradation. This compound utilizes a specific DDR1 inhibitor linked to an E3 ligase ligand, facilitating targeted protein degradation. It exhibits potential applications in elucidating DDR1's role in various cellular processes and disease states, providing valuable insights for therapeutic research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 3081612-73-6 |
| Applications | DDR1 PROTAC Degrader |
| Formula | C43H40F3N9O7 |
| Molecular Weight | 851.83 |
| SMILES | COC1=CC=C(C=C1C#CC2=CN=C(N=C2)NC3CCN(CC3)CCC(NC4=CC=C5C(N(CC5=C4)C6CCC(NC6=O)=O)=O)=O)C(NC7=CC(C(N)=O)=CC(C(F)(F)F)=C7)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.