Fig. 1 · Structure
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PROTAC erf3a Degrader-1
PROTAC erf3a Degrader
PROTAC erf3a Degrader-1 is a potent oral degrader designed to target the erf3a protein. This compound exhibits significant anti-proliferative activity against various cancer cell lines, including 22Rv1, making it a valuable tool in cancer research. PROTAC erf3a Degrader-1 is particularly relevant for studies focused on prostate, ovarian, liver, cervical, and breast cancers, as well as leukemia, facilitating the investigation of targeted protein degradation in these malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 3033871-19-8 |
| Applications | PROTAC erf3a Degrader |
| Formula | C44H52N6O6 |
| Molecular Weight | 760.92 |
| SMILES | O=C(N1[C@@H]2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H](CCC4)C[C@@H]4NC5=CC(NC([C@H]6CC[C@]([C@@]7([H])[C@@](CC8)([H])[C@@]9([C@@](NC(C=C9)=O)([H])CC7)C)([H])[C@]86C)=O)=CC=C5)=C3C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.