PROTAC FLT-3 degrader 1

Catalog No.: A18682

FLT-3 ITD degrader

PROTAC FLT-3 degrader 1

PROTAC FLT-3 degrader 1 Chemical Structure

CAS NO. 2230826-81-8

PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction.

Availability: In stock

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1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

PROTAC FLT-3 degrader 1 is an FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.8 mL 49.01 mL 98.02 mL
0.5 mM 1.96 mL 9.8 mL 19.6 mL
1 mM 0.98 mL 4.9 mL 9.8 mL
5 mM 0.2 mL 0.98 mL 1.96 mL

*The above data is based on the productmolecular weight 1020.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18682
Actions Degrader
CAS No. 2230826-81-8
Formula C52H61N9O9S2
M. Wt 1020.23
Purity >98%
SMILES O=C(N[[email protected]@H](C(C)(C)C)C(N1[[email protected]](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[[email protected]@H](O)C1)=O)CCOCCOCCOC4=CC5=C(N6C(S5)=NC(C7=CC=C(NC(NC8=NOC(C(C)(C)C)=C8)=O)C=C7)=C6)C=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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