Fig. 1 · Structure
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PROTAC(H-PGDS)-7
H-PGDS PROTAC Degrader
PROTAC(H-PGDS)-7 is a targeted protein degradation agent that selectively degrades hematopoietic prostaglandin D synthase (H-PGDS). With a DC50 value of 17.3 pM, it demonstrates potent biological activity in modulating the levels of H-PGDS. This compound is valuable for research applications involving the role of H-PGDS in inflammatory processes and may assist in elucidating therapeutic strategies for related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2761281-50-7 |
| Applications | H-PGDS PROTAC Degrader |
| Formula | C40H38N8O7 |
| Molecular Weight | 742.78 |
| SMILES | O=C(C1CCN(C2=CC=C(NC(C3=CN=C(OC4=CC=CC=C4)N=C3)=O)C=C2)CC1)N5CCN(C6=C(C(N(C7CCC(NC7=O)=O)C8=O)=O)C8=CC=C6)CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.