Fig. 1 · Structure
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PROTAC Her3-binding moiety 1
Her3 Ligand
PROTAC Her3-binding moiety 1 is a ligand designed to selectively target the HER3 protein, facilitating its degradation via the PROTAC (PROteolysis TArgeting Chimeras) technology. This compound plays a critical role in modulating HER3 activity, which is implicated in various cancer pathways. Its application in research includes studying HER3 signaling and developing targeted therapies for HER3-expressing malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1603845-36-8 |
| Applications | Her3 Ligand |
| Formula | C22H21N7O3 |
| Molecular Weight | 431.45 |
| SMILES | NC1=C2C(N(C3CCNCC3)N=C2C4=CC=C(OC5=CC=CC=C5)C([N+]([O-])=O)=C4)=NC=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.