PROTAC HPK1 Degrader-1 is a selective HPK1 degrader that exhibits a DC50 value of 1.8 nM, demonstrating its potency in degrading HPK1. This compound effectively inhibits the phosphorylation of the SLP76 protein, with an IC50 of 496.1 nM. PROTAC HPK1 Degrader-1 serves as a valuable tool for investigating HPK1's role in T cell receptor (TCR) signaling pathways.
PROTAC HPK1 Degrader-1 is a selective HPK1 degrader that exhibits a DC50 value of 1.8 nM, demonstrating its potency in degrading HPK1. This compound effectively inhibits the phosphorylation of the SLP76 protein, with an IC50 of 496.1 nM. PROTAC HPK1 Degrader-1 serves as a valuable tool for investigating HPK1's role in T cell receptor (TCR) signaling pathways.
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