PROTAC JAK1 degrader 1

Name: PROTAC JAK1 degrader 1
Brand: Adooq Bioscience
SKU: A24844
Rating: 5 (288 reviews)

Catalog No.: A24844

JAK1 PROTAC Degrader

PROTAC JAK1 Degrader 1 is a selective PROTAC agent targeting JAK1, exhibiting a DC50 of 214 nM. This compound initiates rapid degradation of JAK1, leading to significant antitumor activity. It serves as a valuable tool for investigating JAK1-related signaling pathways and developing therapeutic strategies for malignancies driven by JAK1 dysregulation.

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PROTAC JAK1 degrader 1 3052553-20-2 JAK1 PROTAC Degrader

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Grouped product items
Size	Price	Stock
5mg	$690.00	In stock
10mg	$1,135.00	In stock
25mg	$2,370.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PROTAC JAK1 Degrader 1 is a selective PROTAC agent targeting JAK1, exhibiting a DC50 of 214 nM. This compound initiates rapid degradation of JAK1, leading to significant antitumor activity. It serves as a valuable tool for investigating JAK1-related signaling pathways and developing therapeutic strategies for malignancies driven by JAK1 dysregulation.

Product Information

Catalog Num	A24844
Formula	C44H41N9O6
Molecular Weight	791.85
CAS Number	3052553-20-2
SMILES	O=C(NCC#N)C1=CC=C(C2=NC(NC3=CC=C(N4CCC(C(NCCCCC#CC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)CC4)C=C3)=NC=C2)C=C1

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