PROTAC K-Ras Degrader-1

Name: PROTAC K-Ras Degrader-1
Brand: Adooq Bioscience
SKU: A23920
Rating: 5 (288 reviews)

Catalog No.: A23920

PROTAC K-Ras Degrader

PROTAC K-Ras Degrader-1 (Compound 518) is a cereblon-based PROTAC that selectively degrades K-Ras, achieving ≥70% degradation efficiency in SW1573 cells. It serves as a valuable tool for studying K-Ras-driven signaling pathways and potential therapeutic strategies in cancer research.

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PROTAC K-Ras Degrader-1 2378258-52-5 PROTAC K-Ras Degrader

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Grouped product items
Size	Price	Stock
1mg	$495.00	In stock
5mg	$1,380.00	In stock
10mg	$2,360.00	In stock
50mg	$7,590.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PROTAC K-Ras Degrader-1 (Compound 518) is a cereblon-based PROTAC that selectively degrades K-Ras, achieving ≥70% degradation efficiency in SW1573 cells. It serves as a valuable tool for studying K-Ras-driven signaling pathways and potential therapeutic strategies in cancer research.

Product Information

Catalog Num	A23920
Formula	C53H62N10O10
Molecular Weight	999.12
CAS Number	2378258-52-5
SMILES	O(C[C@@H]1C[C@@H](OCCOCCOCCOCCNC2=C3C(C(=O)N(C3=O)C4C(=O)NC(=O)CC4)=CC=C2)CN1C)C5=NC(=C6C(CN(CC6)C=7C8=C(C=CC7)C=CC=C8)=N5)N9C[C@H](CC#N)N(C(C=C)=O)CC9
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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