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PROTAC MLLT1 Degrader-1

MLLT1 PROTAC Degrader

PROTAC MLLT1 Degrader-1 is a targeted PROTAC degrader that specifically interacts with MLLT1. This compound effectively inhibits proliferation and viability of acute myeloid leukemia (AML) cells, while also suppressing tumor growth in human AML xenograft models. PROTAC MLLT1 Degrader-1 can be utilized for research focused on MLL-rearranged AML, enabling studies on its oncogene transcriptional regulation and potential therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3111054-37-3
Applications	MLLT1 PROTAC Degrader
Formula	C₃₈H₃₈N₆O₄
Molecular Weight	642.75
SMILES	O=C(CC1)NC(C1N(C2=O)CC3=C2C=CC=C3C#CCCCCC4=CC=C(C(NC5=NC=C6C=C([C@@H]7N(C)CCC7)NC6=C5)=O)C=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.