PROTAC MLLT1 Degrader-1

Catalog No.: A40547
MLLT1 PROTAC Degrader
PROTAC MLLT1 Degrader-1 is a targeted PROTAC degrader that specifically interacts with MLLT1. This compound effectively inhibits proliferation and viability of acute myeloid leukemia (AML) cells, while also suppressing tumor growth in human AML xenograft models. PROTAC MLLT1 Degrader-1 can be utilized for research focused on MLL-rearranged AML, enabling studies on its oncogene transcriptional regulation and potential therapeutic applications.
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Size Stock
5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPROTAC MLLT1 Degrader-1 is a targeted PROTAC degrader that specifically interacts with MLLT1. This compound effectively inhibits proliferation and viability of acute myeloid leukemia (AML) cells, while also suppressing tumor growth in human AML xenograft models. PROTAC MLLT1 Degrader-1 can be utilized for research focused on MLL-rearranged AML, enabling studies on its oncogene transcriptional regulation and potential therapeutic applications.
Product Information
Catalog NumA40547
FormulaC38H38N6O4
Molecular Weight642.75
CAS Number3111054-37-3
SMILESO=C(CC1)NC(C1N(C2=O)CC3=C2C=CC=C3C#CCCCCC4=CC=C(C(NC5=NC=C6C=C([C@@H]7N(C)CCC7)NC6=C5)=O)C=C4)=O
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