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PROTAC PARP/EGFR ligand 1

Active Compound

PROTAC PARP/EGFR ligand 1 is an active compound designed for the synthesis of dual degraders targeting PARP and EGFR through proteolysis-targeting chimera (PROTAC) technology. This reagent facilitates the selective degradation of both target proteins, enabling researchers to investigate their roles in cellular processes and to develop novel therapeutic strategies. Its application in drug discovery and development makes it a valuable tool for studying cancer biology and enhancing targeted therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2661609-57-8
Applications	Active Compound
Formula	C₅₃H₅₆ClF₂N₉O₈
Molecular Weight	1020.52
SMILES	COC(C(OCCCCCC(N[C@@H](COCC#C)C(NCCCCCC(N1CCN(CC1)C(C2=CC(CC(C3=CC=CC=C34)=NNC4=O)=CC=C2F)=O)=O)=O)=O)=C5)=CC6=C5C(NC7=CC(Cl)=C(C=C7)F)=NC=N6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.