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PROTAC PDIA1 degrader 1

PDIA1 PROTAC Degrader

PROTAC PDIA1 Degrader 1 is a PROTAC-based compound designed to selectively target and degrade PDIA1 through the recruitment of the E3 ligase CRBN. It exhibits significant anticancer activity, effectively inhibiting the proliferation of various cancer cell lines. This compound is a valuable tool for researchers investigating the role of PDIA1 in cancer biology and exploring potential therapeutic strategies for targeting this protein.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3024292-21-2
Applications	PDIA1 PROTAC Degrader
Formula	C₄₀H₄₄N₆O₁₂S
Molecular Weight	832.88
SMILES	COC1=C(N(C(C#C)=O)C(C(NCC(NCCOCCOCCOCCNC2=C(C(N(C3C(NC(CC3)=O)=O)C4=O)=O)C4=CC=C2)=O)=O)C5=CC=CS5)C=CC(OC)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.