Fig. 1 · Structure

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PROTAC SARS-CoV-2 Mpro degrader-1

PROTAC

PROTAC SARS-CoV-2 Mpro degrader-1 is a PROTAC-based degrader specifically targeting the main protease of SARS-CoV-2. This compound exhibits broad-spectrum antiviral activity by promoting the degradation of the protease, which is crucial for viral replication. It serves as a valuable tool in antiviral research and therapeutic development against COVID-19.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3029579-46-9
Applications PROTAC
Formula C52H63ClN8O8S
Molecular Weight 995.62
SMILES
ClC1=CC=C(C(N2C3=CC=C(OC)C=C3C(CC(NCCN4CCN(CC4)C(CCC(N[C@H](C(N5[C@@H](C[C@H](C5)O)C(N[C@@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)C(C)(C)C)=O)=O)=O)=C2C)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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