PROTAC SMARCA2 degrader-26 is a specific degrader targeting the SMARCA2 protein. This compound exhibits potent activity, inducing a degradation of 94% for SMARCA2 and 57% for SMARCA4 in VCaP cells. Additionally, PROTAC SMARCA2 degrader-26 demonstrates significant antiproliferative effects, making it a valuable tool for research applications aimed at investigating the roles of SMARCA proteins in cancer and other diseases.
PROTAC SMARCA2 degrader-26 is a specific degrader targeting the SMARCA2 protein. This compound exhibits potent activity, inducing a degradation of 94% for SMARCA2 and 57% for SMARCA4 in VCaP cells. Additionally, PROTAC SMARCA2 degrader-26 demonstrates significant antiproliferative effects, making it a valuable tool for research applications aimed at investigating the roles of SMARCA proteins in cancer and other diseases.
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