PROTAC SOS1 degrader-1

Name: PROTAC SOS1 degrader-1
Brand: Adooq Bioscience
SKU: A63765
Rating: 5 (288 reviews)

Catalog No.: A63765

PROTAC SOS1 degrader

PROTAC SOS1 degrader-1 is a targeted degrader that effectively induces the degradation of SOS1, with an observed DC50 value of 98.4 nM. This compound exhibits significant antiproliferative activity against cancer cells harboring various KRAS mutations. Additionally, PROTAC SOS1 degrader-1 demonstrates notable antitumor effects while maintaining low toxicity, making it a valuable tool for research in cancer therapeutics.

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PROTAC SOS1 degrader-1 2913185-35-8 PROTAC SOS1 degrader

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Grouped product items
Size	Price	Stock
1mg	$440.00	In stock
5mg	$945.00	In stock
10mg	$1,555.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Product Information

Catalog Num	A63765
Formula	C57H76ClFN10O4S
Molecular Weight	1051.79
CAS Number	2913185-35-8
SMILES	O=C([C@H]1N(C([C@@H](NC(CCCCCCCCN2CCN(C3=C4C(N(CC5=CC(C)=C(F)C(C)=C5)C(N6CC7(CNC7)C6)=N4)=CC(Cl)=C3)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C8=CC=C(C9=C(C)N=CS9)C=C8)C

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