Fig. 1 · Structure

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PROTAC SOS1 degrader-7

SOS1 PROTAC Degrader

PROTAC SOS1 degrader-7 is a targeted degradation compound designed to selectively degrade SOS1, a critical regulator in tumorigenesis. This PROTAC exhibits anti-tumor activity by promoting the ubiquitination and subsequent proteasomal degradation of SOS1. It is useful for researchers investigating the effects of SOS1 inhibition in cancer models and exploring potential therapeutic strategies for malignancies involving aberrant SOS1 signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3036155-26-4
Applications SOS1 PROTAC Degrader
Formula C51H64F2N10O4
Molecular Weight 919.12
SMILES
CC1=NN=C(C2=C1C=NC(N3CCN(CC3)C(C4CCN(CC4)CC5CCC6(CCN(CC6)C(C7=CC(N8CCC(NC8=O)=O)=C(C=C7)C)=O)CC5)=O)=C2)N[C@@H](C9=CC=CC(C(F)F)=C9C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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