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PROTAC SOS1 degrader-8

SOS1 PROTAC Degrader

PROTAC SOS1 degrader-8 is a PROTAC-based molecule designed to target and degrade the SOS1 protein. By utilizing a specific SOS1 ligand, a linker, and an E3 ligase ligand, this compound promotes the ubiquitination and subsequent proteasomal degradation of SOS1. Its primary biological activity involves the modulation of downstream signaling pathways associated with oncogenic processes. This reagent is suitable for research applications focused on elucidating the role of SOS1 in cancer biology and exploring novel therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3036155-11-7
Applications	SOS1 PROTAC Degrader
Formula	C₅₀H₆₀ClN₁₁O₄
Molecular Weight	914.54
SMILES	N#CC1=C(C)C([C@@H](C)NC2=NN=C(C)C3=C2C=C(N4CCN(C(C5CCN(CC6CCC7(CCN(C(C8=CC(N9CCC(NC9=O)=O)=C(Cl)C=C8)=O)CC7)CC6)CC5)=O)CC4)N=C3)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.