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PROTAC STAT6 degrader-4

Catalog No.: A36598
STAT6 PROTAC Degrader
PROTAC STAT6 degrader-4 is a potent STAT6 PROTAC degrader with a DC50 of 0.04 nM. It functions by inducing the ubiquitination and subsequent degradation of STAT6, making it an important tool for investigating immune-related diseases. This compound is valuable for researchers studying the role of STAT6 in immune signaling pathways and therapeutic interventions.
PROTAC STAT6 degrader-4 3103198-34-8 STAT6 PROTAC Degrader
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPROTAC STAT6 degrader-4 is a potent STAT6 PROTAC degrader with a DC50 of 0.04 nM. It functions by inducing the ubiquitination and subsequent degradation of STAT6, making it an important tool for investigating immune-related diseases. This compound is valuable for researchers studying the role of STAT6 in immune signaling pathways and therapeutic interventions.
Product Information
Catalog NumA36598
FormulaC54H57FN10O5
Molecular Weight945.09
CAS Number3103198-34-8
SMILESCNC1=CC(N(C=C1)C2=CC=NC3=C2C=C(N3C)CN4CC=C(CC4)C5=C(C=C(C=C5F)C(N(C6=CC=C(C=C6)C7CCN(CC7)CC8=CC9=C(N(C(N9C)=O)C%10CCC(NC%10=O)=O)C=C8)C)=O)C)=O
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PROTAC > PROTAC Degrader