Fig. 1 · Structure

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PROTAC STAT6 degrader-4

STAT6 PROTAC Degrader

PROTAC STAT6 degrader-4 is a potent STAT6 PROTAC degrader with a DC50 of 0.04 nM. It functions by inducing the ubiquitination and subsequent degradation of STAT6, making it an important tool for investigating immune-related diseases. This compound is valuable for researchers studying the role of STAT6 in immune signaling pathways and therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3103198-34-8
Applications STAT6 PROTAC Degrader
Formula C54H57FN10O5
Molecular Weight 945.09
SMILES
CNC1=CC(N(C=C1)C2=CC=NC3=C2C=C(N3C)CN4CC=C(CC4)C5=C(C=C(C=C5F)C(N(C6=CC=C(C=C6)C7CCN(CC7)CC8=CC9=C(N(C(N9C)=O)C%10CCC(NC%10=O)=O)C=C8)C)=O)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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